People / Rios Laboratory

Contact

Maribel Rios, Ph.D.
Assistant Professor of Neuroscience
Phone: (617) 636-2748
Fax: 617-636-2413
maribel.rios@tufts.edu

Search for recent publications by Maribel Rios

Research Interests

Regulation of affective behavior, food intake and metabolic function by brain derived neurotrophic factor; neurodegeneration; obesity and mood disorders; mouse genetics.

Also see the complete research description.

Lab Members

Sarah Teillon, Graduate student in Neuroscience
TJ Unger, Graduate student in Physiology
Shabrine Daftary-Bussiere, Postdoctoral Associate
Joshua Cordeira, Graduate student in Neuroscience
German Calderon, Research Technician
Anders Marcussen, Visiting Graduate Student, Univ. of Copenhagen

Selected Publications

Unger TJ, Calderon G, Bradley LC, Sena-Estevez M, Rios M. (2007). Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. In Press Journal of Neuroscience

Graham DL, DiLeone RJ, Rios M, Self DW. (2007). Dynamic BDNF activity in the Nucleus Accumbens with cocaine use increases self-Administration and relapse. Nature Neuroscience 10, 1029 – 1037

Rios M, Lambe E, Liu RJ, Teillon S, Liu J, Akbarian S, Roffler-Tarlov S, Jaenisch R, Aghajanian G. (2006). Severe deficits in 5-HT2A-mediated neurotransmission in BDNF conditional mutant mice. Journal of Neurobiology 66:408-420

Chan JP*, Unger TJ*, Byrnes J, Rios M. (2006). Examination of behavioral deficits triggered by targeting Bdnf in fetal or postnatal brains of mice. Neuroscience Journal 142(1):49-58

Berton O, McClung C, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos C, Rios M, Monteggia LM. Self DW, Nestler EJ. (2006) Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311:864-8

Zhao J, Seereeman A, Nassar MA, Levato A, Pezet S, Hathaway G, Morenilla-Palao C, Fitzgerald M, McMahon SB, Rios M, Wood J. (2006) Nociceptor-derived Brain derived-neurotrophic factor regulates acute and inflammatory but not neuropathic pain. Molecular and Cellular Neuroscience Mar;31(3):539-48

Lyckman A, Fan G, Rios M, Jaenisch R, and Sur, M. (2005) Normal eye-specific patterning of retinal inputs to subcortical visual nuclei in the absence of brain derived neurotrophic factor. Visual Neuroscience 22: 27-36

Portbury AL, Chandra R, McMillian MK, Groelle M, Elias A, Herlong JR, Rios M, Roffler-Tarlov S, and Chikaraishi DM. (2003) Catecholamines act via a beta-like adrenergic receptor to maintain fetal heart rate and survival. Am J Physiol Heart Circ Physiol 284: H2069-77

Rios M*, Akbarian S*, Liu RJ, Jones K, Tesarrollo L, Nestler E, Aghajanian G, Jaenisch R. (2002) Brain derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. Journal of Neuroscience. 22:4153-62

Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan R, Jaenisch R. (2001) Conditional deletion of brain derived neurotrophic factor leads to obesity and hyperactivity. Molecular Endocrinology 15:1748-1757

Roffler-Tarlov S.and Rios M. Catecholamines before nervous activity. In: Handbook on Brain and Behavior in Human Development. A. Gramsbergen and A. Kalverboer, Eds. Kluwer Academic Publishers. (2001)

Tian H, Habecker B, Guidry G, Gurtan A, Rios M, Roffler-Tarlov S, Landis SC. (2000) Catecholamines Are Required for the Acquisition of Secretory Responsiveness by Sweat Glands. Journal of Neuroscience 19:7362-7369

Bates B, Rios M, Trumpp A, Chen C, Fan G, Bishop JM, Jaenisch R. (1999) Neurotrophin-3 is required for proper cerebellar development. Nature Neuroscience 2:115-7

Rios M, Habecker B, Sasaoka T, Eisenhofer G, Tian H, Landis S, Chikaraishi D, Roffler-Tarlov S. (1999) Catecholamine synthesis is mediated by tyrosinase in the absence of tyrosine hydroxylase. Journal of Neuroscience 19:3519-26

*Authors contributed equally to the work